CBD is found primarily in extractions from the hemp plant. It’s sold in gels, gummies, oils, supplements, extracts, and more.
THC is the main psychoactive compound in marijuana. It can be consumed by smoking marijuana. It’s also available in oils, edibles, tinctures, capsules, and more.
Both compounds interact with your body’s endocannabinoid system but they have very different effects.
Despite their similar chemical structures, CBD and THC don’t have the same psychoactive effects. In fact, CBD is a nonpsychoactive compound. That means it doesn’t produce the “high” associated with THC.
THC binds with the cannabinoid 1 (CB1) receptors in the brain. It produces a high or sense of euphoria.
CBD binds very weakly, if at all, to CB1 receptors. In fact, it can interfere with the binding of THC and dampen the psychoactive effects.
CBD and THC have many of the same medical benefits. They can provide relief from several of the same conditions. However, CBD doesn’t cause the euphoric effects that occur with THC. Some people may prefer to use CBD because of the lack of this side effect.
| |
CBD |
THC |
| Produce a "high" |
No |
Yes |
| Illegal |
Yes* |
Yes* |
| Side Effects |
Almost None |
Psychoactive Side Effects |
| Shows on Drug Test |
Yes** |
Yes |
| Pain Reliever |
Yes |
Yes |
| Reduces Nausea |
Yes |
Yes |
| Eases Migraines |
Yes |
Yes
|
| Reduces Anxiety |
Yes |
Yes |
| Increases Appetite |
No |
Yes |
| Decreases Seizures |
Yes |
No |
| Anti-inflammatory |
Yes |
Yes |
*Both CBD and THC are illegal federally. However, some states have laws that make them legal for medical or recreational purposes, or both.
**CBD isn’t always detected but hemp products may contain trace amounts of THC. They may show up in high enough concentrations to produce a positive drug test.